Leading Health and Life Sciences in Nova Scotia

Adaptiiv Wins $100K Health Challenge

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Halifax-based Adaptiiv Medical Technologies has won the Nova Scotia Health Authority’s first Health Challenge pitch competition, bagging a $100,000 prize.

Announced in February and hosted by innovation hub Volta, the Health Challenges are a series of five events aimed at identifying technologies to help modernize Nova Scotia’s aging and understaffed healthcare system. Friday’s competition was focused exclusively on cancer-related innovations.

In addition to the cash prize, the NSHA has promised to consider adopting Adaptiiv’s technology for use in the provincial medical system.

“Through this challenge, we know that we have created this space that’s supportive or collaborative in nature,” said Dr. Gail Tomblin Murphy, who is the NSHA’s vice president of research, innovation and discovery, and chief nurse executive. She added that the display of innovation shows “that the support and strength to draw from our private partners is making a difference.”

Adaptiiv sells equipment and software for 3D printing specialized bolus devices – pieces of polymer placed on patients’ bodies to target radiation therapy during cancer treatment.

ENTREVESTOR: Adaptiiv Partners With Italy’s EZB

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Adaptiiv Medical Technologies Inc., the Halifax company that uses 3D printing to improve cancer treatment, has further extended its international reach by partnering with Italian peer Eckert & Ziegler BEBIG, or EZB.

EZB specializes in products used in brachytherapy, which applies radioactive sources directly to or into tumors while sparing the surrounding healthy tissue. For the patient, this means shorter treatment periods, fewer side effects and a faster recovery.

The two companies announced Sunday they will test and align their systems to provide an integrated workflow for cancer centers to create 3D-printed brachytherapy applicators customized to each patient. They believe the collaboration will demonstrate that 3D printing can provide clinically viable solutions that improve treatment and patient care.

“This is a significant milestone for us,” said Adaptiiv CTO Alex Dunphy in the press release.“Collaborating with the team at EZB has allowed us to continue to make significant strides towards improving the standard of care using a patient-specific approach in brachytherapy. The successful alignment of our systems will demonstrate that 3D printing can be used to provide a clinically viable solution in brachytherapy treatment.”

Adaptiiv’s software provides practitioners with a turn-key solution that enables 3D printing of patient-specific uniform thickness bolus, modulated bolus for MERT (modulated electron radiation therapy), High Dose Rate (HDR) surface brachytherapy and other potential ancillary devices. Adaptiiv software fully integrates with existing treatment planning systems and compliments the existing radiation treatment workflows. Each module of Adaptiiv’s software is designed to solve challenges faced by today’s therapists, dosimetrists, and oncologists such as air gaps in bolus, sparing healthy tissues in electron treatments and the fabrication of complex brachy devices. The company’s software is already used in CanadaAustraliaIsraelIreland and England. “This 510(k) clearance uniquely positions Adaptiiv to fuel the growth of personalized medicine through elegantly simple, intuitive technology,” notes Adaptiiv CEO, Peter Hickey. “Our technology platform is the first of its kind and allows users to easily design patient-specific devices that can be 3D printed and used during radiation treatment.” Coupled with the recent announcement of its global distribution agreement with CIVCO Radiotherapy, the leading global provider of high quality, innovative, patient-centric radiotherapy solutions, Adaptiiv continues to make significant strides in the battle against cancer and transforming novel and experimental ideas into real world applications. About Adaptiiv Adaptiiv Medical Technologies Inc. (formerly 3D Bolus Inc.) is the definitive 3D technology platform for radiation oncology. Headquartered in Halifax, Nova Scotia, Canada Adaptiiv is shaping the future of patient-specific healthcare through innovation and collaboration with leading Cancer centres throughout the world..  Adaptiiv is ISO 13485 certified and has received a CE Mark.  Our technology is based on the work of Dr. James Robar, Chief of Medical Physics at the Nova Scotia Health Authority, in partnership with Dalhousie University in Halifax, Canada.
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ACOA: Adaptiiv Medical Technologies Perfecting Customized Medical Software

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Government of Canada supports targeted marketing plan, regulatory approvals and research commercialization  May 14, 2018 – Halifax, NS – Atlantic Canada Opportunities Agency Helping Atlantic Canadian businesses succeed by fostering greater innovation through the commercialization of research creates well-paying jobs and improves the lives of all Canadians. That is why the Government of Canada is supporting Adaptiiv Medical Technologies’ revolutionary ideas in the creation of patient-specific boluses to improve the delivery of more effective and accurate radiation doses to targeted areas. Andy Fillmore, Parliamentary Secretary for the Minister of Democratic Institutions and Member of Parliament for Halifax, announced a $328,943 investment of behalf of the Honourable Navdeep Bains, Minister of Innovation, Science and Economic Development, and Minister responsible for the Atlantic Canada Opportunities Agency (ACOA). The contribution is being made through ACOA’s Business Development Program, which supports small and medium-sized companies’ innovation to improve competitiveness in export markets. The assistance will help Adaptiiv Medical Technologies obtain regulatory approval to expand into new markets in the United States, and to execute a new marketing plan featuring promotional materials and a demonstration video to showcase the company’s software to aid with its increased market reach. The funds will also help Adaptiiv finalize the commercialization of its High Dynamic Range (HDR) Imaging-Surface Bracatherapy Module, which is a form of treatment where sealed radiation is placed inside or next to the area requiring treatment. Bracatherapy is commonly used to treat cervical, prostate, breast and skin cancer, and can also be used to treat tumors in many other body sites. The investment builds on the commitments made by the Government of Canada and the four Atlantic Provinces to drive economic growth in Atlantic Canada through the Atlantic Growth Strategy. The Strategy supports targeted investments in initiatives that build on the region’s competitive advantages, such as its strong export potential and skilled labour to expand business activities between the region and international markets.

Quotes

“Canada is a country of innovators. Curiosity, courage, and creativity are what lead to the kind of innovations and technologies that improve our daily lives and drive our economy, and our country, forward. Adaptiiv Medical Technologies, a pioneer in medical solutions to deliver better, more accurate treatment, is an example of the adaptability we need to foster in our home-grown businesses to maintain our competitive edge in the global economy.” –       The Honourable Navdeep Bains, Minister of Innovation, Science and Economic Development and Minister responsible for ACOA “For businesses to grow and create good, well-paying jobs, they must be supported in their endeavors to turn their new ideas into products that can compete in the global marketplace. Adaptiiv Medical Technologies is well-placed to help countless individuals with its technologies that can improve medical treatments, providing a strong foundation on which to build new partnerships with both clients and consumers.” –       Andy Fillmore, Parliamentary Secretary to the Minister of Democratic Institutions and Member of Parliament for Halifax “Adaptiiv’s software enables clinicians to design and 3D print accessories for radiation therapy treatment. Our goal is to democratize the delivery of patient-specific treatment. To that end, Adaptiiv is thrilled with the support it has received from the Canadian Government and Atlantic provinces and their continued role in encouraging innovation as we work to provide our patient-specific solution to the global radiotherapy market.” –       Peter Hickey, CEO of Adaptiiv Medical Technologies 

Quick facts

    • A conventional bolus is a flat piece of rubber-like material placed on top of the patient’s skin to increase the radiation dose to the skin and to the tissues right below it. However, conventional boluses are unable to accommodate or correct for anatomical irregularities, making them less than optimal.
    • Conventional boluses often have air cavities between the bolus and skin, which can cause an under dose of medication.
    • Adaptiiv overcomes the challenges of conventional boluses and other accessories currently used in radiation therapy.
    • Adaptiiv is a software application that fully integrates with existing treatment methods, using 3D printing to produce treatment accessories on demand.
    • Adaptiiv’s algorithms automatically calculates a customized design that changes the surface shape of the bolus to allow for tailoring of dose distribution. The application produces objects that are accepted directly into the planning software and used to accurately develop a treatment plan.
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ENTREVESTOR: N.S. firm promoting new cancer treatment

See original story here The executive team of Halifax-based Adaptiiv, fresh with a recent round of financing, is attending an international radiotherapy conference in Barcelona this week to announce a new distribution partnership. Formerly known as 3DBolus, Adaptiiv is a company that has been gaining notice in Halifax biotech circles for a couple of years, even though it just released its first public statement this week. The company has developed software that works with 3D printers to produce a personalized bolus — a plastic fitting used in radiation therapy. Adaptiiv has launched three different products, booked sales in six countries and raised almost $3 million in equity funding. Last week Adaptiiv announced it had signed a distribution agreement with Iowa-based CIVCO Radiotherapy, which will give it sales representatives in all main districts of North America. “This is a special company,” CEO Peter Hickey said in an interview Tuesday before jetting off to the Estro Conference in Spain. “When I was first approached by the team I initially thought, ‘This isn’t for me,’ because I was in IT. But the team, especially (board member) Bruce Ross, kept driving home the point that this is a software play. It was one of those cases where I fell in love with the company.” Hickey is best known in the community as a serial entrepreneur in the IT space, most recently for being the CEO of Oris4, which shut down two years ago. In Adaptiiv, he’s teamed up with James Robar, chief of medical physics at the Nova Scotia Health Authority and director of medical physics graduate programs at Dalhousie University, and serial tech entrepreneur Alex Dunphy. What Adaptiiv does is revolutionize the use of a bolus in radiation therapy. A bolus is a piece of plastic placed over the cancerous area, assuming the tumours are close to or in the skin. The radiation hits the bolus, builds up and then is transferred into the tumour. There can be no air pockets between the bolus and the skin, which complicates matters given that every body is unique. Hospitals using the Adaptiiv product buy a system that includes 3D printers with special filaments, so unique boluses customized to each patient can be printed within seconds. They can be reused as the patient receives repeated radiation dosages. Or if the patient’s body shape changes over the course of multiple treatments, the medical staff can print off another bolus quickly. The company has received its CE Mark certification, meaning it can sell into several countries including members of the European Union. It already has clients in the U.K., Ireland, Israel, Australia and Canada. It has applied for its 510k approval in the U.S. and Hickey said it hopes to receive approval “soon.” Adaptiiv recently closed a round of funding which included investment from Alexander Capital in New York, an investment boutique that makes direct investments and rounds up angel investors to back companies. Hickey said Adaptiiv has now raised almost $3 million and is planning a larger raise once it receives its 510k approval. Adaptiiv has three products in the market, including one that helps to prevent healthy organs from being damaged during radiation therapy. With nine employees (soon to be 12), the company continues to develop new products. “We have a pipeline with some really great innovation,” said Hickey. “That’s what we are. We’re a Nova Scotian-based innovation company that’s producing solutions to problems that people haven’t solved yet.”]]>